For analysis on how the latest escalation in the Middle East will affect a host of issues in the region, Amna Nawaz speaks with Miad Maleki at the Foundation for Defense of Democracies and David Makovsky at the Washington Institute for Near East Policy.

The World Health Organization said Wednesday that the fight against Ebola in the Democratic Republic of Congo is "catching up" with the spread of the virus. But health officials warn the crisis is far from over with more than 340 cases already confirmed and the outbreak crossing into neighboring Uganda. Chris Ocamringa reports from DRC's capital Kinshasa.

The U.S. military started what it called "self-defense strikes" against Iran for the downing of an Army helicopter near the Strait of Hormuz. President Trump said the two crew members were both "safe and uninjured" after the Apache helicopter went down while on patrol off the coast of Oman. Geoff Bennett discussed the latest with Dan Lamothe of The Washington Post.

As U.S.-Iran talks show little sign of progress, commercial traffic through the Strait of Hormuz remains sharply reduced, raising concerns about global energy markets and supply chains. Geoff Bennett speaks with energy analyst Daniel Yergin, vice chairman of S&P Global, for more on what a prolonged disruption could mean around the world.